| ORAL:ACUTE MYELOGENOUS & MYELOMONOCYTIC LEUKAEMIA:Maintenance dose vary between 1.5 & 2.5mg/kg/day as a single dose. Dosage of Mercaptopurine should be reduced to 1/4 of the usual dose if allopurinol is given concurrently.
ACUTE LYMPHATIC LEUKAEMIA INCLUDING LYMPHOCYTIC & LYMPHOBLASTIC SUBTYPES:INDUCTION OF REMISSION & MAINTENANCE:2.5mg/kg/day. May be continued for several weeks. If after 4 weeks there is no response, dose may be increased to 5mg/kg/day. |